References.
Rate of ADE

Adverse drug events caused by serious medication administration errors.

Kale A1, Keohane CAMaviglia SGandhi TKPoon EG.

Conclusions:

Unintercepted potential ADEs at the medication administration stage can cause serious patient harm. At hospitals where 6 million doses are administered per year, about 4000 preventable ADEs would be attributable to medication administration errors annually.

Cost of ADE (Australian) 

The incidence and cost of adverse events in Victorian hospitals 2003–04

Jonathon P Ehsani, Terri Jackson and Stephen J Duckett

Med J Aust 2006; 184 (11): 551-555. || doi: 10.5694/j.1326-5377.2006.tb00378.x
Published online: 5 June 2006

Main outcome measures: 

Cost of each patient admission (“admitted episode”), length of stay and mortality.

 

Results: 

During the designated timeframe, 979 834 admitted episodes were in the sample, of which 67 435 (6.88%) had at least one adverse event. Patients with adverse events stayed about 10 days longer and had over seven times the risk of in-hospital death than those without complications. After adjusting for age and comorbidity, the presence of an adverse event adds $6826 to the cost of each admitted episode. The total cost of adverse events in this dataset in 2003–04 was $460.311 million, representing 15.7% of the total expenditure on direct hospital costs, or an additional 18.6% of the total inpatient hospital budget.

 

Conclusion: 

Adverse events are associated with significant costs. Administrative datasets are a cost-effective source of information that can be used for a range of clinical governance activities to prevent adverse events.

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